Research Themes

Cell-Cell Communication

The mammalian heart is an organ comprising of heterogeneous cell types. In this project, we are exploring mechanisms by which diverse cellular...

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Cell States Regeneration, Differentiation & Dedifferentiation

Our lab is making use of the human pluripotent stem cells derived cardiomyocytes (hPSC-CM) system as a model to study cardiac development and...

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Circular RNA

Circular RNA Circular RNAs (circRNAs) belong to a class of non-coding RNA. They are single-stranded RNA circularized as a result from a...

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High-throughput Screening

High-throughput Screening

In this project, we have been working closely with the Centre of High Throughput Phenomics (CHiP) at the Genome Institute, which is a valuable...

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Chromatin architecture & Epigenetics

  The DNA chromatin is folded into In this project, we have been working to unravel how the epigenome regulates cardiac development and...

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Long non-coding RNA

Next generation sequencing (NGS) has revealed a complex landscape of transcription across the non-coding genome, allowing the discovery of novel...

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Technical capabilities

Whole exon sequencing

Whole exome sequencing technology allows us to efficiently sequence protein coding region...

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Bioinformatics & Computing

Our lab research revolves critically around bioinformatic analysis and integration of...

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Engineered Heart Tissue

The generation of miniature Engineered Heart tissue (Hansen/Eder et al. 2010) involves a...

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Animal

Animal work is a bedrock of the Foo lab research. Any adequate study of the mammalian heart...

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CRISPR/CAS9 Genome Editing

The Foo lab is using CRISPR/Cas9 tools in many different ways both in vitro & in vivo...

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Viruses

Our lab currently relies heavily on the Adeno-associated viruses (AAV) platform for in vivo...

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Histology

Our studies with mouse and human hearts frequently require detailed histological...

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RNA Seq

RNA-seq is the next-generation sequencing based technique that we use to analyse cellular...

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Differentiation

In the Foo lab, we are continuously generating hES-derived cardiomyocytes as an in-vitro...

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Single Cell

The adult mammalian heart is a highly heterogeneous organ. Whole-transcriptome...

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Hi-C

Chromosome capture conformation with high throughput sequencing is a molecular biology...

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ChipSeq

Chromatin Immunoprecipitation (ChIP) combined with NGS sequencing is the method of choice...

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Funding Support

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