Chromatin Immunoprecipitation (ChIP) combined with NGS sequencing is the method of choice for identifying genome wide DNA binding sites for transcription factors and other DNA associated proteins.

The application of ChIP-seq reveals gene regulation events that play a role in the heart and cardiovascular diseases. By understanding the gene regulation and genome organisation of the heart in health and disease, we seek to discover novel biomarkers or molecular pathways that may lead to new therapeutic options for cardiovascular diseases.



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