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Cell States Regeneration, Differentiation & Dedifferentiation

Started June 21, 2019 170 0

Our lab is making use of the human pluripotent stem cells derived cardiomyocytes (hPSC-CM) system as a model to study cardiac development and disease pathophysiology.

 

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Differentiation and de-differentiation

Differentiation
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De-differentiation
Adult mouse cardiomyocytes (CMs) cultured in vitro breakdown and re-build the sarcomere (Ackers-Johnson, Matthew, et al. Circulation research 119.8 (2016): 909-920.).
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Ackers-Johnson, Matthew, et al. Circulation research 119.8 (2016): 909-920.
Matt (in vitro model) Wilson (Bioinformatics analysis) Vinh (Sghrt) Peter (Animal work) Tuan (Animal work) Zenia (RNA sequencing)

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