Animal

Animal work is a bedrock of the Foo lab research. Any adequate study of the mammalian heart has to be performed in the context of a live animal, and rodents are the best models with which to carry out in vivo studies of the heart. Our lab has established robust and consistent surgical models of disease (Transverse Aortic Constriction, Myocardial Infarction, Drug Minipump). Phenotypes may be assessed through a variety of imaging modalities such as Ultrasound (echocardiography), PET-Scan, MRI and IVIS. Supported by the animal facility at NUS, the team has also conducted metabolic studies involving exercise related equipment. 

The animal team, led by Peter Li, also aims to ensure safety and regulatory protocols are established with local regulatory bodies of AVA, IACUC and NUS. The team works to the guidelines from AAALAC and is supported by the vets and support staff from Comparative Medicine, NUS. Mice are frequently imported for the team. At the current time, the lab is maintaining 19 transgenic/knockout mouse strains). We have experience importing mice from established companies such as Jacksons Lab, Invivos, Charles River and other research institutes around the world.