Long non-coding RNA

Next generation sequencing (NGS) has revealed a complex landscape of transcription across the non-coding genome, allowing the discovery of novel epigenetic regulators involved in cardiac specification and maturation, as well as cardiac regeneration. Other than transcription factors and chromatin modifiers, long non-coding RNAs (lncRNA) have gained attention as important modulators of cardiac biology and pathophysiology.

Our lab has established robust differentiation and trans-differentiation protocols aimed at uncovering new lncRNAs involved in cardiac development and disease.


CM specification and maturation


Singheart paper
Albert_ Cardaic differentation and maturation,

Vinh_Cardaic regenaration,




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