Whole exome sequencing technology allows us to efficiently sequence protein coding region of the genome and identify a common or rare coding...
Read moreBioinformatics & Computing
Our lab research revolves critically around bioinformatic analysis and integration of myriad datasets generated from state-of-the-art...
Read moreEngineered Heart Tissue
The generation of miniature Engineered Heart tissue (Hansen/Eder et al. 2010) involves a construction of fibrinogen and thrombin as a hydrogel...
Read moreAnimal
Animal work is a bedrock of the Foo lab research. Any adequate study of the mammalian heart has to be performed in the context of a live animal...
Read moreSurgery
CRISPR/CAS9 Genome Editing
The Foo lab is using CRISPR/Cas9 tools in many different ways both in vitro & in vivo. The various CRISPR techniques have deployed gene...
Read moreViruses
Our lab currently relies heavily on the Adeno-associated viruses (AAV) platform for in vivo gene delivery. AAVs enables the delivery of the gene...
Read moreHistology
Our studies with mouse and human hearts frequently require detailed histological examination. Hearts are routinely processed into either cryo or...
Read moreRNA Seq
RNA-seq is the next-generation sequencing based technique that we use to analyse cellular gene expression profiles. Depending on the purpose of...
Read moreDifferentiation
In the Foo lab, we are continuously generating hES-derived cardiomyocytes as an in-vitro model of human heart development and disease. This...
Read moreSingle Cell
The adult mammalian heart is a highly heterogeneous organ. Whole-transcriptome RNA-sequencing of bulk heart tissue reveals considerable insight...
Read moreHi-C
Chromosome capture conformation with high throughput sequencing is a molecular biology method used to analyze the 3D chromatin architecture in a...
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